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Table of Contents

Overview

Links

Additional Help

Overview

Discovery Studio is a single unified, easy-to-use, graphical interface for powerful drug design and protein modeling research. Discovery Studio contains both established gold-standard applications (e.g., Catalyst, MODELER, CHARMm, etc.) with years of proven published results, as well as and cutting-edge science to address today’s drug discovery challenges. Discovery Studio is built on the Pipeline Pilot Enterprise Server™ operating platform, allowing seamless integration of protein modeling, pharmacophore analysis, and structure-based design, as well as third-party applications.

Discovery Studio also includes the Insight II package, which was previously available as a stand-alone application.

Note: The Pipeline Pilot server for this package is pipelinepilot.its.unc.edu.

Availability on the Research Computing Clusters

Research Computing Cluster: Longleaf
Default Version: 2020 (Longleaf)
Installed Version(s): 2020 and 2019 (Longleaf)

Note: You must be a “tcsh” or “csh” user to benefit from the full functionality of this package on a Research Computing server.

Installing and Setting up the Discovery Studio Environment on a Windows Machine

You can also install Discovery Studio locally on your Windows PC. Research Computing provides the installation binary:

  • The binary for Discovery Studio can be copied from Longleaf to your Windows machine from:
     /nas/longleaf/apps/discoverystudio/2020/dist/BIOVIA_2020.DS2020Client.exe
  • Once the binary is downloaded, double-click the file to unpack the installation executable.
  • Run the Autorun program in the unpacked directory to start installation.
  • Once Discovery Studio is installed, make the license manager point to the following license server for campus users: license0.its.unc.edu; port number: 1715.
  • More information regarding installation of Discovery Studio can be found in the README document in the unpacked installation directory.

Links

  • Discovery Studio main information page and application areas from Accelrys.
  • Details of programs installed in Discovery Studio.
  • Case studies of applications of Discovery Studio applied to Life Science Research.

Additional Help

Research Computing home page